neuronal Ca+2 sensor 1; NCS-1; frequenin homolog; frequenin-like protein; frequenin-like ubiquitous protein (NCS1, FLUP, FREQ)

Function

• neuronal calcium sensor
• regulates G protein-coupled receptor phosphorylation
• regulates GRK1
• may carry out functions similar to calmodulin
• interacts with KCND2

Cofactor: binds 3 Ca+2 ions

Compartment

• associated with Golgi stacks
• found in:
  • post-synaptic densities of dendrites
  • pre-synaptic nerve terminal at neuromuscular junctions

More general terms

• Ca+2 sensor or Ca+2 sensing receptor
• myristoylated protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23413
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23413
• OMIM: https://mirror.omim.org/entry/603315
• UniProt: http://www.uniprot.org/uniprot/P62166.html