surfeit locus protein 4 (SURF4, SURF-4)

Function

• may play a role in maintenance of the endoplasmic reticulum-Golgi intermediate compartment & of the Golgi
• found in a complex composed at least of SURF4, TMED2 & TMED10
• may interact with LMAN1

Structure

• the di-Lys motif confers endoplasmic reticulum localization for type 1 membrane proteins
• belongs to the SURF4 family

Compartment

• endoplasmic reticulum membrane
• multi-pass membrane protein
• endoplasmic reticulum-Golgi intermediate compartment membrane
• Golgi
• cycles between the endoplasmic reticulum & the Golgi

Alternative splicing

named isoforms=2

More general terms

• transmembrane 5 protein
• mitochondrial protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6836
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6836
• OMIM: https://mirror.omim.org/entry/185660
• UniProt: http://www.uniprot.org/uniprot/O15260.html