transmembrane emp24 domain-containing protein 2 (membrane protein p24A, TMED2, RNP24)

Function

• role in the budding of coatomer-coated & other coated vesicles
• may bind cargo molecules to collect them into budding vesicles
• interacts with ARFGAP1, inhibiting its GTPase-activating

Structure

• belongs to the EMP24/GP25L family
• contains 1 GOLD domain

Compartment

• cytoplasmic vesicle membrane
• COPI-coated vesicle membrane
• Golgi-derived coatomer-coated vesicles

More general terms

• EMP24/GP25L family protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q15363.html