p53-regulated apoptosis-inducing protein 1 (p53AIP1) (TP53AIP1)
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Function
- may play role in mediating p53/TP53-dependent apoptosis
- overexpression causes dissipation of mitochondrial membrane potential
Compartment
Alternative splicing
named isoforms=4
Expression
- only found to be expressed in thymus
- induced by p53/TP53
- induced by DNA damage (p53-dependent)
More general terms
References
- ↑ Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y, Taya Y. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell. 2000 Sep 15;102(6):849-62. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11030628
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=63970
- ↑ UniProt http://www.uniprot.org/uniprot/Q9HCN2.html