3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)

Function

• role in valine catabolism
• catalyzes the NAD-dependent, reversible oxidation of 3-hydroxybutyrate to methylmalonate

Structure

homdimer

Compartment

mitochondria

Laboratory

• 3-hydroxyisobutyrate dehydrogenase in fibroblasts

More general terms

• dehydrogenase
• mitochondrial protein
• oligomerizing protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11112
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:11112
• OMIM: https://mirror.omim.org/entry/608475
• UniProt: http://www.uniprot.org/uniprot/P31937.html