stress-70 protein, mitochondrial; 75 kD glucose-regulated protein; GRP 75; heat shock 70 kD protein 9; peptide-binding protein 74; PBP74; mortalin; MOT (HSPA9, GRP75, HSPA9B)

Function

• implicated in the control of cell proliferation & terminal differentiation
• may also act as a chaperone
• phosphorylated upon DNA damage, probably by ATM or ATR
• interacts with FXN

Structure

belongs to the heat shock protein 70 family

Compartment

mitochondria

More general terms

• heat shock protein [hsp]-70 family
• chaperonin; chaperone
• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/P38646.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3313
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3313
• OMIM: https://mirror.omim.org/entry/600548