homeobox protein unc-4 homolog (homeobox protein Uncx4.1, UNCX, UNCX41)

Function

• transcription factor involved in somitogenesis & neurogenesis
• required for the maintenance & differentiation of particular elements of the axial skeleton
• may act upstream of PAX9
• plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation & to deliver hormones for control of peripheral functions (putative)

Structure

• belongs to the paired homeobox family, Unc-4 subfamily
• contains 1 homeobox DNA-binding domain

Compartment

nucleus (putative)

More general terms

• nuclear protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3402
• UniProt: http://www.uniprot.org/uniprot/A6NJT0.html