paired box protein PAX9 (PAX9)

Function

• transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull & larynx as well as distal limbs
• interacts with JARID1B

Structure

contains 1 paired domain

Compartment

nucleus

Pathology

• defects in PAX9 are a cause of oligodontia

More general terms

• paired box protein (PAX)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5083
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5083
• OMIM: https://mirror.omim.org/entry/167416
• UniProt: http://www.uniprot.org/uniprot/P55771.html