protein DERPC (Decreased expression in renal & prostate cancer protein, DERPC)
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Function
- potential tumor suppressor
- inhibits prostate tumor cell growth, when overexpressed
Compartment
Expression
- ubiquitously expressed
- expressed in kidney, skeletal muscle, testis, heart > prostate
Pathology
- expression is significantly diminished in renal cancer & prostate cancer
- no differential expression in breast cancer cells, between lobular carcinoma & normal lobules
- found in a common chromosomal region of deletion in breast cancer
Genetics
- gene encoding this protein shares overlapping exons with CTF8 (UniProt Q8WV66 deleted from database Aug 2010)
Notes
UniProt :accession Q8NDH8 deleted from database May 2010