crossover junction endonuclease EME2 (EME2)

Function

• interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures
• interacts with MUS81

Structure

belongs to the EME1/MMS4 family

Compartment

nucleus (probable)

Alternative splicing

named isoforms=2

More general terms

• endodeoxyribonuclease
• nuclear protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1973
• UniProt: http://www.uniprot.org/uniprot/A4GXA9.html