transcriptional adapter 2-beta (ADA2-like beta protein, ADA2-beta, TADA2B, ADA2B)

Function

• coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2
• interacts with GCN5L2, SMARCA4, SMARCE1 & PAX5
• component of the TFTC-HAT complex

Structure

• contains 1 SANT domain
• contains 1 ZZ-type Zn+2 finger

Compartment

nucleus (probable)

Alternative splicing

named isoforms=3

More general terms

• nuclear protein
• zinc finger protein

Component of

• TFTC-HAT complex (TATA-binding protein-free TAF complex, TBP-free TAFII complex, TFTC)

Database

• OMIM: https://mirror.omim.org/entry/608790
• UniProt: http://www.uniprot.org/uniprot/Q86TJ2.html