synaptonemal complex central element protein 2 (central element synaptonemal complex protein 1, SYCE2 CESC1)

Function

• major component of the transverse central element of synaptonemal complexes
• requires SYCP1 for incorporation into the central element
• role in synaptonemal complexe assembly, stabilization & recombination (putative)
• found in a complex with SYCP1 & SYCE1
• interacts with SYCP1 & SYCE1 (putative)

Structure

• homodimer
• belongs to the SYCE family

Compartment

• nucleus, associates with chromatin
• in prophase 1 stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes
• found only where the chromosome cores are synapsed
• colocalizes with SYCE1 in the central elements

More general terms

• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6PIF2.html