breast carcinoma amplified sequence 3 (GAOB1, Maab1 protein, BCAS3)
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Structure
- contains 3 WD repeats
Compartment
Alternative splicing
named isoforms=5
Expression
- expressed in stomach, liver, lung, kidney, prostate, testis, thyroid, adrenal, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leucocyte, mammary epithelial cells
Pathology
- overexpressed in most breast cancer cell lines
- a chromosomal translocation t(17;20)(q23;q13) involving BCAS3 with BCAS4 may be a cause of breast cancer
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q9H6U6.html
- ↑ Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Genes/BCAS3ID766.html