TSC22 domain family protein 1 (transforming growth factor beta-1-induced transcript 4 protein, regulatory protein TSC-22, TGFB-stimulated clone 22 homolog, cerebral protein 2, TSC22D1 TGFB1I4 TSC22, hucep-2)

Function

• transcriptional repressor
• acts on the C-type natriuretic peptide (CNP) promoter
• homodimer or heterodimer; can form an heterodimer with TSC22D4

Compartment

cytoplasm, nucleus

Expression

• widely expressed in fetal & adult tissues
• in aortic endothelial cells, induced by cytokines, including TGFB.

More general terms

• nuclear protein

Database

• OMIM: https://mirror.omim.org/entry/607715
• UniProt: http://www.uniprot.org/uniprot/Q15714.html