small nuclear RNA-activating protein-50; SNAPc 50 kDa subunit; proximal sequence element-binding transcription factor beta subunit; PSE-binding factor beta subunit; PTF beta subunit (SNAP50, SNAPC3)

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Function

part of the SNAPc complex
binds to proximal sequence element (PSE), a non-TATA-box basal
recruits TBP & BRF2 to the U6 snRNA TATA box
phosphorylated upon DNA damage, probably by ATM or ATR

Compartment

More general terms

Component of

small nuclear RNA-activating protein complex (SNAPc)

References

↑ Henry RW, Sadowski CL, Kobayashi R, Hernandez N. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature. 1995 Apr 13;374(6523):653-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7715707
↑ UniProt http://www.uniprot.org/uniprot/Q92966.html
↑ OMIM https://mirror.omim.org/entry/602348

Database

Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6619
OMIM: https://mirror.omim.org/entry/602348
UniProt: http://www.uniprot.org/uniprot/Q92966.html
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6619

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