NF-Y protein chain C {gamma}; CAAT-box DNA-binding protein subunit C; CCAAT-binding transcription factor subunit C; transactivator HSM-1/2 (NFYC)

Function

• component of nuclear factor Y
• stimulates the transcription of various genes by recognizing & binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin & beta-actin genes
• NFYB & NFYC must interact & dimerize for NFYA association & DNA binding

Structure

belongs to the NFYC/HAP5 subunit family

Compartment

nucleus

Alternative splicing

named isoforms=3

More general terms

• nuclear protein
• protein subunit

Component of

• nuclear factor Y; CAAT-box DNA-binding protein; CCAAT-binding transcription factor; CBF, (NFY)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4802
• OMIM: https://mirror.omim.org/entry/605344
• UniProt: http://www.uniprot.org/uniprot/Q13952.html