mastermind-like family protein

From Aaushi
Jump to navigation Jump to search

Introduction

Transcriptional coactivators for notch receptors.

Contain N-terminal basic domain which binds the intracellular domain of notch (ICN) & C-terminal transcriptional activation domain.

More general terms

More specific terms

References

  1. Wu L et al. Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors. Mol Cell Biol 22:7688-700, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12370315
  2. Maillard I & Pear WS. Notch and cancer: best to avoid the ups and downs. Cancer Cell 3:203-5, 2003 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12676578