EGF-like domain-containing protein 7 (multiple EGF-like domain protein 7, multiple epidermal growth factor-like domain protein 7, vascular endothelial statin, VE-statin, NOTCH4-like protein, ZNEU1, EGFL7, MEGF7, UNQ187/PRO1449)
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Function
- regulates vascular tubulogenesis in vivo
- inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration
- promotes endothelial cells adhesion to substrate in vitro
Structure
- contains 2 EGF-like domains
- contains 1 EMI domain