salusin-alpha

Function

• salusin-alpha & salusin-beta are produced by proteolytic processing of prosalusin
• salusin-alpha & salusin-beta may be endocrine &/or paracrine factors able to increase intracellular Ca+2 & induce cell mitogenesis
• salusins may also be potent hypotensive peptides
• amidation of salusin-alpha(29-Gly) by peptidylglycine alpha- amidating monooxygenase, PAM, converts Lys-241-Gly-242 to Lys-241-NH2 & gives raise to salusin-alpha
• salusin-alpha & salusin-beta are only produced from an alternatively spliced mRNA of TOR2A, isoform 4

More general terms

• secreted protein

Additional terms

• prosalusin (torsin-2A, torsin family 2 member A, [Contains: Salusin-alpha; Salusin-beta], TOR2A)