vacuolar ATP synthase subunit H; V-ATPase H subunit; vacuolar proton pump H subunit (ATP6V1H)

Function

• component of the peripheral V1 complex of vacuolar ATPase
• subunit H activates ATPase activity ofvacuolar ATPase & couples ATPase activity to proton flow
• interacts with AP2M1.

Alternative splicing

named isoforms=2

Expression

widely expressed

Pathology

• interacts with HIV-1 Nef protein

More general terms

• protein subunit

Component of

• vacuolar ATP synthase (v ATPase) or endomembrane proton pump

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51606
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5160
• OMIM: https://mirror.omim.org/entry/608861
• UniProt: http://www.uniprot.org/uniprot/Q9UI12.html