vacuolar ATP synthase (v ATPase) or endomembrane proton pump

Function

• responsible for acidifying a variety of intracellular compartments in eukaryotic cells

Structure

• heteromultimeric enzyme composed of at least 13 subunits
  • peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' & d)
  • ATP6V0A1

More general terms

• adenosine triphosphatase (ATPase)
• multisubunit protein

Additional terms

• vacuole