ferritin light chain; ferritin L subunit (FTL)

Function

• light chain of ferritin

Structure

• belongs to the ferritin family
• contains 1 ferritin-like diiron domain

Pathology

• defects in FTL are the cause of hereditary hyperferritinemia-cataract syndrome (mutations in the iron responsive element (IRE) of the FTL gene)
• defects in FTL are the cause of neuroferritinopathy

More general terms

• protein subunit

Component of

• ferritin

Database

• UniProt: http://www.uniprot.org/uniprot/P02792.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2512
• OMIM: https://mirror.omim.org/entry/134790
• OMIM: https://mirror.omim.org/entry/600886
• OMIM: https://mirror.omim.org/entry/606159