coagulation factor XIII B subunit; protein-glutamine gamma-glutamyltransferase B chain; transglutaminase B chain; fibrin-stabilizing factor B subunit (F13B)
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Function
- regulatory B chain of coagulation factor XIII
- not catalytically active
- thought to stabilize the coagulation factor XIII A subunits & regulate the rate of transglutaminase formation by thrombin
Structure
contains 10 Sushi (CCP/SCR) domains
Pathology
- defects in F13B are associated with F13B deficiency
More general terms
Component of
References
- ↑ Bottenus et al Biochemistry 29:11195 1990
- ↑ SHMPD; The Singapore human mutation and polymorphism database http://shmpd.bii.a-star.edu.sg/gene.php?genestart=F&genename=F13B+%40+FXIIIB
- ↑ Wikipedia; Note: factor XIII entry http://en.wikipedia.org/wiki/factor_XIII
- ↑ SeattleSNPs http://pga.gs.washington.edu/data/f13b/
- ↑ UniProt http://www.uniprot.org/uniprot/P05160.html