rhophilin-1 (GTP-Rho-binding protein 1, RHPN1)

Function

• binds specifically to GTP-Rho
• target for Rho
• no enzymatic activity
• may interact with cytoskeletal component upon Rho binding or relay Rho signal to other proteins

Structure

• contains 1 BRO1 domain
• contains 1 PDZ (DHR) domain
• contains 1 REM (Hr1) repeat

Alternative splicing

named isoforms=2

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/601031
• UniProt: http://www.uniprot.org/uniprot/Q8TCX5.html