protein PTDSR; phosphatidylserine receptor (PTDSR, JMJD6, KIAA0585)

Introduction

Originally thought to be phosphatidylserine receptor with role in apoptosis

Function

• role in embryogenesis
• hematopoietic differentiation
• regulation of macrophage cytokine responses

Structure

• contains 1 JmjC domain

Compartment

nucleus

Alternative splicing

named isoforms=3

Expression

• expressed in heart, skeletal muscle, kidney > brain, placenta, lung, liver, pancreas, spleen, thymus, prostate, testis, ovary
• up-regulated in many patients with chronic pancreatitis

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/604914
• UniProt: http://www.uniprot.org/uniprot/Q6NYC1.html