pleckstrin homology Sec7 & coiled-coil domains-binding protein (cytohesin-binding protein HE, CYBR, cytohesin binder and regulator, cytohesin-interacting protein, PSCDBP, CYTIP)

Function

• binds to cytohesin-1 (PSCD1)
• modifies activation of ARFs by PSCD1
• sequesters PSCD1 in the cytoplasm
• induced by TNF alpha & LPS

Compartment

cytoplasm, may also be membrane-associated

Expression

• expressed in lymph nodes, thymus, spleen, lung, peripheral blood leukocytes, bone marrow

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/604448
• UniProt: http://www.uniprot.org/uniprot/O60759.html