SH2 domain-containing protein 1B; EWS/FLI1-activated transcript 2; EAT-2 (SH2D1B, EAT2)

Function

• plays a role in controlling signal transduction through at least 4 receptors, CD84, CD150, CD229 & CD244, expressed
• on the surface of professional antigen-presenting cells
• binds to the phosphorylated receptors CD84, CD150, CD229 & CD244
• does not bind to non-phosphorylated CD150

Structure

contains 1 SH2 domain

Alternative splicing

named isoforms=2

More general terms

• SH2 domain-containing protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=117157
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:117157
• OMIM: https://mirror.omim.org/entry/608510
• UniProt: http://www.uniprot.org/uniprot/O14796.html