muskelin (MKLN1)

Function

• acts as a mediator of cell spreading & cytoskeletal responses to the extracellular matrix component thrombospondin 1
• interacts with the C-terminal tail of the prostaglandin EP3 receptor alpha isoform (putative)
• interacts with RANBP9 part of a complex consisting of RANBP9, MKLN1 & C20orf11

Structure

• contains 1 CTLH domain
• contains 6 kelch repeats
• contains 1 LisH domain

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=2

More general terms

• other protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4289
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4289
• OMIM: https://mirror.omim.org/entry/605623
• UniProt: http://www.uniprot.org/uniprot/Q9UL63.html