serine/threonine protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2 (STK17B, DRAK2)

Function

• acts as a positive regulator of apoptosis
• interacts with CHP causing CHP to translocate from the Golgi to the nucleus (putative)

Structure

• belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily
• contains 1 protein kinase domain

Compartment

nucleus

Expression

• highly expressed in placenta, lung, pancreas
• lower expression in heart, brain, liver, skeletal muscle & kidney

More general terms

• serine/threonine kinase
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9262
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9262
• OMIM: https://mirror.omim.org/entry/604727
• UniProt: http://www.uniprot.org/uniprot/O94768.html