myosin light chain kinase smooth musle (MLCK, MYLK, telokin, kinase-related protein, KRP)

Function

• smooth muscle contraction via phosphorylation of Ser in the N-terminus of myosin light chains
• growth of astrocytic processes
• transmitter release at synapses of sympathetic ganglion neurons
• fibroblast apoptosis
• precursor to several splice products: telokin, non-muscle MLCK isozyme & smooth muscle MLCK isozyme
• responsible for smooth muscle contraction via phosphorylation of specific Ser of myosin light chains

More general terms

• myosin light chain kinase (MLCK, MYLK)

Database

• OMIM: https://mirror.omim.org/entry/600922
• UniProt: http://www.uniprot.org/uniprot/Q15746.html