Ca+2/calmodulin-dependent protein kinase type 1B; CaM kinase 1 beta; CaM kinase 1B; CaM-K1 beta; CaMK1-beta; pregnancy up-regulated non-ubiquitously-expressed CaM kinase (PNCK)

Function

• Ca+2/calmodulin-dependent protein kinase belonging to a proposed Ca+2-triggered signaling cascade
• in vitro phosphorylates CREB1 & SYN1/synapsin 1
• phosphorylates & activates CAMK1 (putative)
• activated by Ca+2/calmodulin (putative)
• phosphorylated by CAMKK1 (probable)

Structure

• belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily
• contains 1 protein kinase domain

Compartment

• cytoplasm, nucleus (putative)

Alternative splicing

named isoforms=4

More general terms

• Ca+2/calmodulin-dependent protein kinase (CaM kinase)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=139728
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:139728
• OMIM: https://mirror.omim.org/entry/300680
• UniProt: http://www.uniprot.org/uniprot/Q6P2M8.html