transcription factor COE3; early B-cell factor 3; EBF-3; olf-1/EBF-like 2; O/E-2; OE-2 (EBF3, COE3)

Function

• transcriptional activator
• recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (putative)
• forms either a homodimer or a heterodimer with a related family member (putative)

Structure

• belongs to the COE family
• contains 1 IPT/TIG domain

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2; long, short

Expression

expressed in brain

More general terms

• COE family transcription factor
• human longevity protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=253738
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:253738
• OMIM: https://mirror.omim.org/entry/607407
• UniProt: http://www.uniprot.org/uniprot/Q9H4W6.html