forkhead box protein F2; forkhead-related transcription factor 2; FREAC-2; forkhead-related activator-2; drosophila forkhead homolog-like 6 (FOXF2)

Function

• probable transcription activator for a number of lung-specific genes
• interacts with the transcription factors TBP & TFIIB

Structure

• contains 1 fork-head DNA-binding domain
• two activation domains, AD1 & AD2, C-terminal of (& distinct from) the forkhead domains are necessary for transcriptional activation

Compartment

nucleus

Expression

lung, placenta

More general terms

• forkhead family transcription factor

Database

• OMIM: https://mirror.omim.org/entry/603250
• UniProt: http://www.uniprot.org/uniprot/Q12947.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2295