early growth response protein 4; EGR-4; AT133 (EGR4)
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Function
- transcriptional regulator. recognizes & binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG)
- activates the transcription of target genes whose products are required for mitogenesis & differentiation (putative)
Structure
- belongs to the EGR C2H2-type Zn+2-finger protein family
- contains 3 C2H2-type Zn+2 fingers
Compartment
nucleus (probable)
Expression
induced by PHA/PMA or by serum
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q05215.html
- ↑ Gashler A and Sukhatme VP Early growth response protein 1 (EGR-1): prototype of a zinc- finger family of transcription factors. Prog Nuclei Acid Res Mol Biol 1995, 50:191 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7754034
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1961
- ↑ UniProt http://www.uniprot.org/uniprot/Q05215.html