ets2 proto-oncogene protein; protein C-ets-2 (ETS2)

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Function

required for meiotic maturation of oocytes

Structure

belongs to the ETS family
translation product of alternatively spliced transcript of c-ets
contains 1 ETS DNA-binding domain
contains 1 PNT (pointed) domain

Compartment

Expression

induced following macrophage differentiation & T-cell activation

More general terms

Ets family protein

References

↑ Macleod K, Leprince D, Stehelin D. The ets gene family. Trends Biochem Sci. 1992 Jul;17(7):251-6. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1502727
↑ Chen ZQ, Burdett LA, Seth AK, Lautenberger JA, Papas TS. Requirement of ets-2 expression for Xenopus oocyte maturation. Science. 1990 Dec 7;250(4986):1416-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2255913
↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2114
↑ UniProt http://www.uniprot.org/uniprot/P15036.html

Database

UniProt: http://www.uniprot.org/uniprot/P15036.html
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2114
OMIM: https://mirror.omim.org/entry/164740
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2114

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