transcription regulator protein BACH2 (BTB & CNC homolog 2, BACH2)
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Function
- transcriptional regulator
- acts as repressor or activator
- binds to Maf recognition elements (MARE)
- role in coordinating transcription activation & repression by MAFK
- forms heterodimer with Maf-related transcription factors
Structure
- belongs to the bZIP family, CNC subfamily
- contains 1 BTB domain (POZ domain)
- contains 1 bZIP domain
Compartment
Expression
B-cell specific