transcription regulator protein BACH1; BTB & CNC homolog 1; HA2303 (BACH1)

Function

• transcriptional regulator that acts as repressor or activator
• binds, in-vitro, to NF-E2 binding sites
• role in coordinating transcription activation & transcriptional repression by MAFK

Structure

• belongs to the bZIP family, CNC subfamily
• contains 1 BTB/POZ domain
• contains 1 bZIP domain

Compartment

nucleus (putative)

More general terms

• basic leucine zipper (bZIP) family protein
• DNA-binding protein
• phosphoprotein

Additional terms

• Fanconi anemia group J protein; protein FACJ; ATP-dependent RNA helicase BRIP1; BRCA1-associated C-terminal helicase 1; BRCA1-interacting protein C-terminal helicase 1; BRCA1-interacting protein 1 (BRIP1, BACH1, FANCJ)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=571
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:571
• OMIM: https://mirror.omim.org/entry/602751
• UniProt: http://www.uniprot.org/uniprot/O14867.html