CCAAT/enhancer binding protein (C/EBP, CBF, NF-Y protein)
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Function
- DNA-binding protein that recognizes two different motifs:
- may regulate growth arrest in differentiating cells
- different C/EBP isoforms form homodimers & heterodimers
More general terms
More specific terms
- CCAAT-binding transcription factor-1 subunit A (CBF-A), enhancer factor 1A (ef1-A) or DNA-binding protein B (DBPB)
- CCAAT/enhancer-binding protein-alpha; C/EBP alpha (CEBPA)
- CCAAT/enhancer-binding protein-beta; C/EBP beta; nuclear factor NF-IL6; transcription factor 5 (CEBPB, TCF5, PP9092)
- CCAAT/enhancer-binding protein-delta; C/EBP delta; nuclear factor NF-IL6-beta; NF-IL6-beta (CEBPD)
- CCAAT/enhancer-binding protein-epsilon; C/EBP epsilon (CEBPE)
- CCAAT/enhancer-binding protein-gamma; C/EBP gamma (CEBPG)
Additional terms
References
- ↑ Landschulz WH, Johnson PF, McKnight SL. The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite. Science. 1989 Mar 31;243(4899):1681-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2494700
- ↑ Dwarki VJ, Montminy M, Verma IM. Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. EMBO J. 1990 Jan;9(1):225-32. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2136830
- ↑ Umek et al Science 251:288 1991