CCAAT/enhancer-binding protein-alpha; C/EBP alpha (CEBPA)

Function

• C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters & the enhanced core homology common to many enhancers
• binds DNA as a dimer & can form stable heterodimers with C/EBP beta & C/EBP gamma
• interacts with UBN1
• interacts with HBV protein X

Structure

• belongs to the bZIP family, C/EBP subfamily
• contains 1 bZIP domain

Compartment

nucleus

More general terms

• CCAAT/enhancer binding protein (C/EBP, CBF, NF-Y protein)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1050
• OMIM: https://mirror.omim.org/entry/116897
• UniProt: http://www.uniprot.org/uniprot/P49715.html