transcription factor AP-4; activating enhancer-binding protein 4; class C basic helix-loop-helix protein 41; bHLHc41 (TFAP4, BHLHC41)

Function

• transcription factor
• activates both viral & cellular genes by binding to the symmetrical DNA sequence 5'-CAGCTG-3'
• efficient DNA binding requires dimerization with another bHLH protein

Structure

• homodimer
• contains 1 basic helix-loop-helix (bHLH) domain

Compartment

nucleus

More general terms

• basic helix loop helix (bHLH) family transcription factor
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7023
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7023
• OMIM: https://mirror.omim.org/entry/600743
• UniProt: http://www.uniprot.org/uniprot/Q01664.html