high affinity immunoglobulin epsilon receptor subunit beta; FcERI; IgE Fc receptor subunit beta; Fc epsilon receptor I beta-chain; membrane-spanning 4-domains subfamily A member 2 (MS4A2, APY, FCER1B, IGER)

Function

• beta subunit of IgE receptor

Structure

belongs to the MS4A family

Compartment

membrane

Expression

• found on the surface of mast cells & basophils

Polymorphism

• variant Glu-237 has been found to be present in about 5.3% of a 1004 individuals population sample in Australia; it seems to be a risk factor for atopic dermatitis & asthma

More general terms

• transmembrane 4 protein
• protein subunit
• phosphoprotein

Component of

• immunoglobulin E [IgE] receptor or Fc epsilon [IgE] receptor-1

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2206
• OMIM: https://mirror.omim.org/entry/147138
• UniProt: http://www.uniprot.org/uniprot/Q01362.html