chloride intracellular channel protein 1; chloride channel ABP; nuclear chloride ion channel 27; NCC27; regulatory nuclear chloride ion channel protein; hRNCC (CLIC1, G6, NCC27)

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Function

Structure

  • members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane & functions as chloride channel
  • a conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion
  • belongs to the chloride channel CLIC family
  • contains 1 GST C-terminal domain

Compartment

Expression

Notes

More general terms

References

Database