CD159a; NKG2-A/NKG2-B type II integral membrane protein; NKG2-A/B-activating NK receptor; NK cell receptor A; CD159 antigen-like family member A; killer cell lectin-lik receptor subfamily C member 1 (KLRC1, NKG2A)

Function

• plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells & some cytotoxic T-cells
• can form disulfide-bonded heterodimer with CD94

Structure

contains 1 C-type lectin domain

Compartment

membrane

Alternative splicing

named isoforms=2; A,B

Expression

natural killer cells

More general terms

• killer cell lectin-like receptor C subfamily or NKG2 receptor
• CD antigen
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3821
• OMIM: https://mirror.omim.org/entry/161555
• UniProt: http://www.uniprot.org/uniprot/P26715.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=