C-C motif chemokine 27; CC chemokine ILC; cutaneous T-cell-attracting chemokine; CTACK; Eskine; IL-11 R-alpha-locus chemokine; skinkine; small-inducible cytokine A27 (CCL27, ILC, SCYA27)

Function

• chemotactic factor
• chemotactic for skin-associated memory T-cells
• may play a role in mediating homing of lymphocytes to cutaneous sites
• binds to CCR10
• heparin avidly promotes oligomerization

Structure

• monomer, dimer, & tetramer
• belongs to the intercrine beta (chemokine CC) family

Compartment

secreted

Expression

• expressed in testis, thymus, placenta, ovary & skin

More general terms

• CC chemokine; beta chemokine

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10850
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10850
• OMIM: https://mirror.omim.org/entry/604833
• UniProt: http://www.uniprot.org/uniprot/Q9Y4X3.html