C-C motif chemokine 24; CK-beta-6; eosinophil chemotactic protein 2; Eotaxin-2; myeloid progenitor inhibitory factor 2; MPIF-2; small-inducible cytokine A24 (CCL24, MPIF2, SCYA24)

Function

• chemotactic for resting T-lymphocytes, & eosinophils
• has lower chemotactic activity for neutrophils
• not chemotactic for monocytes or activated lymphocytes
• strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line
• binds to CCR3

Structure

• N-glycosylated
• belongs to the intercrine beta (chemokine CC) family

Compartment

secreted

Expression

• activated monocytes & activated T-cells

More general terms

• CC chemokine; beta chemokine

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6369
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6369
• OMIM: https://mirror.omim.org/entry/602495
• UniProt: http://www.uniprot.org/uniprot/O00175.html