CD42c; platelet glycoprotein Ib beta chain; GP-Ib beta; GPIb-beta; GPIbB; antigen CD42b-beta (GP1BB)

Function

• component of glycoprotein Ib which in turn is a component of platelet vWF receptor GP-Ib-V-IX

Structure

contains 1 LRR (leucine-rich) repeat

Compartment

membrane

Alternative splicing

named isoforms=2

Expression

• expressed in heart & brain
• expressed in platelets, megakaryocytes

Pathology

• defects in GP1BB are a cause of Bernard-Soulier syndrome

More general terms

• CD42
• phosphoprotein

Component of

• platelet glycoprotein 1b

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2812
• OMIM: https://mirror.omim.org/entry/138720
• OMIM: https://mirror.omim.org/entry/231200
• UniProt: http://www.uniprot.org/uniprot/P13224.html