PDZ & LIM domain protein 1; Elfin; LIM domain protein CLP-36; C-terminal LIM domain protein 1 (PDLIM1, CLIM1, CLP36)

Function

• cytoskeletal protein
• may act as an adapter that brings other proteins (like kinases) to the cytoskeleton
• interacts with alpha-actinins 1, 2 & 4

Structure

• contains 1 LIM Zn+2-binding domain
• contains 1 PDZ domain (DHR domain)

Compartment

• cytoplasm (putative)
• cytoskeleton (putative)
• associates with the actin stress fibers (putative)

Expression

• strongly expressed in the heart & skeletal muscle
• moderately expressed in the spleen, small intestine, colon, placenta, & lung
• a lower level expression is seen in liver, thymus, kidney, prostate & pancreas
• not found in the brain, testis, ovary, or peripheral blood leukocytes

More general terms

• PDZ & LIM domain protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9124
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9124
• OMIM: https://mirror.omim.org/entry/605900
• UniProt: http://www.uniprot.org/uniprot/O00151.html