pleckstrin homology domain-containing family K member 1 (rhotekin-2, PLEKHK1, RTKN2)

Function

• may play an important role in lymphopoiesis

Structure

contains 1 PH domain

Alternative splicing

named isoforms=3

Expression

• expressed in lymphocytes, CD4 positive T-cells & bone marrow-derived cells
• also expressed in lung, colon, thymus & brain
• up-regulated in cells resistant to 25-hydroxycholesterol

More general terms

• pleckstrin homology domain containing family

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IZC4.html