ankyrin repeat domain-containing protein 12; ankyrin repeat-containing cofactor 2; GAC-1 protein (ANKRD12, ANCO2, KIAA0874)

Function

• may recruit HDACs to the p160 coactivators - nuclear receptor complex to inhibit ligand-dependent transactivation
• interacts with the PAS region of the p160 coactivators

Structure

contains 3 ANK repeats

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• nuclear protein
• ankyrin repeat domain protein (ANKRD)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23253
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23253
• OMIM: https://mirror.omim.org/entry/610616
• UniProt: http://www.uniprot.org/uniprot/Q6UB98.html