Golgin subfamily A member 3; Golgi complex-associated protein of 170 kDa; GCP170; Golgin-160 (GOLGA3)

Function

• Golgi auto-antigen
• probably involved in maintaining Golgi structure
• cleaved by caspases in apoptotic cells
• interacts with GOLGA7
• isoform 1 interacts with GOPC
  • isoform 3 does not interact with GOPC

Structure

• homodimer
• extended rod-like protein with coiled-coil domains

Compartment

• cytoplasm
• Golgi, Golgi stack membrane

Alternative splicing

• named isoforms=3
• intron retention

Expression

• expressed in all tissues tested
• expressed in liver, testis, lung, heart, salivary gland & kidney

More general terms

• golgin (GOLGI autoantigen)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2802
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2802
• OMIM: https://mirror.omim.org/entry/602581
• UniProt: http://www.uniprot.org/uniprot/Q08378.html